CASLINK for One-Step Structure Searching in CAS REGISTRY, MARPAT, and CAplus

Use the CASLINK database cluster for quick, easy, and cost-effective substance searching in REGISTRY, MARPAT, and CAplus. Search an exact structure or a structure fragment, and you automatically get a single set of literature and patent references to specific substances or Markush structures that match the structure query. (HCASLINK is available if you prefer to search HCAplus.)

1.  Enter CASLINK. You are automatically connected to REGISTRY, MARPAT, and CAplus.
2. Upload the structure from CAS IP Finder. An L-number is assigned for the structure.
3. Conduct a sample (default) search (SSS) on the structure query (L1). Sample searches are automatically run in REGISTRY (L2) and MARPAT (L3).
4. Display a structure in the free SCAN format from one of the answer sets (L2) to verify that your query is retrieving appropriate answers.
   
   
   
   
5. Conduct a full substructure search. The following steps are automatically performed:

   • Search the full REGISTRY database (L4).
   • Search the full MARPAT database (L5).
   • Search for references to specific substances in CAplus (L6).
   • Remove duplicates (L7).

6. Display some answers, eg., the title (TI) and corporate source (CS) form the first answer from each file.

7. Combine your structure search with text terms. The appropriate searches are automatically performed in the CASLINK databases.

   PATENT/DT limits the
   answer to patents

   Example 2. Find published references, including patent claims, to the following phenyl piperdino analog of ovalicin.

1. Upload the structure
2. Enter file CASLINK
3. Conduct an exact sample (EXA SAM) structure search in CASLINK. CASLINK automatically performs a sample exact structure search in REGISTRY and a sample closed substructure search (CSS) in MARPAT.
4. Conduct an exact full structure search in CASLINK.
5. Display the desired bibliographic data (title) and first hit Markush structure (FHIT) to view the retrieved structure. The hit structure fragments are highlighted.                                                      This relevant patent would not have been found if the exact search were conducted only in REGISTRY.

Solution images are included for illustrative purposes only. Edited for brevity. Your experience may vary based on recent enhancements or product license.